UK laboratory buying guide
Platinum II PCR master mix alternatives: compare Yeasen 10108 and 10167
Compare YEASEN 10108 genotyping mix and 10167 rapid PCR mix with Platinum II or OneTaq. Both YEASEN mixes include loading dye. View pack sizes and UK prices below.
YEASEN products and GBP prices ex VAT
Compare pack sizes and current prices, or open a product for the full manufacturer details.
| Catalogue no. | Pack size | Price ex VAT | Select a pack |
|---|---|---|---|
| 10108ES03 | 1 mL 100 T | £18.82£0.188/reaction£22.58 incl. VAT | View pack |
| 10108ES08 | 5 × 1 mL 500 T | £94.11£0.188/reaction£112.93 incl. VAT | View pack |
| 10108ES50 | 50 × 1 mL 5000 T | £668.34£0.134/reaction£802.01 incl. VAT | View pack |
| 10108ES60 | 100 × 1 mL 10000 T | £1,336.68£0.134/reaction£1,604.02 incl. VAT | View pack |
| Catalogue no. | Pack size | Price ex VAT | Select a pack |
|---|---|---|---|
| 10167ES03 | 1 mL | £28.23£28.23/mL£33.88 incl. VAT | View pack |
| 10167ES08 | 5 × 1 mL | £117.64£23.53/mL£141.17 incl. VAT | View pack |
| 10167ES50 | 50 × 1 mL | £742.60£14.85/mL£891.12 incl. VAT | View pack |
What matters when choosing
Platinum II PCR master mix is available in Green and colourless formats. This guide distinguishes the catalogue numbers and compares them with Yeasen 10108 and 10167, which both include tracking dye. Check the intended endpoint-PCR application and the exact format before choosing a product.
| Decision factor | Reference product | Yeasen option | Buying consideration |
|---|---|---|---|
| Reference identity | Platinum II 14001012/14001013/14001014 are Green formats. 14000012/14000013/14000014 are colourless. | 10108 is labelled With Dye; 10167 includes a red tracking dye. | A coloured mix is not the same format as a colourless one. Check downstream detection and purification requirements.Invitrogen Platinum II Hot-Start Green PCR Master Mix 14001012Invitrogen Platinum II Hot-Start PCR Master Mix 14000012Yeasen 10108: product specificationsYeasen 10167: product specifications |
| Pack format and purpose | Both referenced Platinum II formats are 2× PCR master mixes. | 10108 is a 2× PCR genotyping mix; 10167 is a 2× universal PCR mix with genotyping applications. | The 2× concentration helps identify the format but does not establish identical chemistry, assay performance or instructions.Invitrogen Platinum II Hot-Start Green PCR Master Mix 14001012Invitrogen Platinum II Hot-Start PCR Master Mix 14000012Yeasen 10108: product specificationsYeasen 10167: product specifications |
| Hot-start information | The selected Platinum II products are labelled Hot-Start. | The current YEASEN manual identifies 10108 as a ligand-modified hot-start Taq formulation; 10167 uses antibody-modified hot-start Taq. | Refer to the current manual linked on each product page for its specification.Invitrogen Platinum II Hot-Start PCR Master Mix 14000012YEASEN 10108 manual EN20251208Yeasen 10108: product specificationsYeasen 10167: product specifications |
Reference products and catalogue numbers
Find your current product, then review the relevant YEASEN option. These products serve related applications but have different formulations and instructions.
- Invitrogen Platinum II Hot-Start Green PCR Master Mix
14001012 · 14001013 · 14001014
- Invitrogen Platinum II Hot-Start PCR Master Mix
14000012 · 14000013 · 14000014
- NEB OneTaq Hot Start 2X Master Mix with Standard Buffer
M0484S · M0484L
- NEB OneTaq Hot Start Quick-Load 2X Master Mix
M0488S · M0488L
Questions before switching products
Can I replace a colourless PCR mix with a mix containing dye?
Check the intended downstream application first. Included dye changes the format. Review the selected manufacturer's stated compatibility with your downstream application.
Section linkShould I use this guide for a Q5 high-fidelity comparison?
Use our dedicated Q5 and high-fidelity PCR guide for that decision. Routine PCR or genotyping suitability does not establish comparable proofreading performance.
Section linkWhich reference should I put on a quotation request?
Include the exact catalogue number, whether a coloured or colourless mix is required, the intended application and the pack size. We can then identify a relevant Yeasen option without treating all PCR mixes as equivalent.
Section linkManufacturer sources
We supply the Yeasen products listed above. This guide compares manufacturer specifications; it is not an independent performance study. Reference products are identified for comparison and are not offered for sale here.
Find product documents and sources, or read our UK buying guide for ordering and delivery information.
Consult the current product documents for your application.
- Yeasen 10108: product specifications
- Yeasen 10167: product specifications
- YEASEN 10108 manual EN20251208
- Invitrogen Platinum II Hot-Start Green PCR Master Mix 14001012
- Invitrogen Platinum II Hot-Start PCR Master Mix 14000012
Products are for research use only. Third-party trade marks belong to their respective owners; no affiliation or endorsement is implied. Similar applications do not establish identical composition, performance or compatibility.
Related buying guides
- Q5 PCR Alternatives UK: Compare Yeasen 10166
Compare Yeasen 10166 for high-fidelity PCR with NEB Q5 M0491 and M0494. Check enzyme versus master-mix formats and GBP prices ex VAT.

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