UK laboratory buying guide
GeneRuler DNA ladder alternatives: compare Yeasen 1 kb, 50 bp and DL5000
Compare YEASEN GoldBand DL5000, 1 kb and 50 bp ladders with GeneRuler and other DNA markers. Check the band positions and loading volumes for the exact product, then choose a pack size.
YEASEN products and GBP prices ex VAT
Compare pack sizes and current prices, or open a product for the full manufacturer details.
| Catalogue no. | Pack size | Price ex VAT | Select a pack |
|---|---|---|---|
| 10504ES60 | 100 T | £29.71£0.297/load£35.65 incl. VAT | View pack |
| 10504ES80 | 10 × 100 T | £207.93£0.208/load£249.52 incl. VAT | View pack |
GoldBand™ DL5000 DNA Marker| Catalogue no. | Pack size | Price ex VAT | Select a pack |
|---|---|---|---|
| 10510ES60 | 100 T | £33.42£0.334/load£40.10 incl. VAT | View pack |
| 10510ES80 | 10 × 100 T | £259.92£0.260/load£311.90 incl. VAT | View pack |
GoldBand™ 1 kb DNA ladder| Catalogue no. | Pack size | Price ex VAT | Select a pack |
|---|---|---|---|
| 10515ES60 | 100 T | £40.85£0.409/load£49.02 incl. VAT | View pack |
| 10515ES80 | 10 × 100 T | £263.63£0.264/load£316.36 incl. VAT | View pack |
GoldBand™ 50 bp DNA LadderWhat matters when choosing
A 1 kb or 50 bp ladder name does not define a universal band pattern. Yeasen 10510 extends to 12,000 bp, while the referenced GeneRuler 1 kb ready-to-use ladder ends at 10,000 bp. For shorter fragments, compare the individual band positions and reference bands before ordering.
| Decision factor | Reference product | Yeasen option | Buying consideration |
|---|---|---|---|
| 1 kb ladders | GeneRuler SM0313/SM0314: 14 bands, 250–10,000 bp; ready-to-use. | 10510: 13 bands, 250–12,000 bp; stronger 1,500 and 4,000 bp reference bands. | Compare spacing near the fragment of interest. A longer upper range does not mean the intermediate bands are identical.Thermo Scientific GeneRuler 1 kb DNA Ladder, ready-to-use SM0313Yeasen 10510: product specifications |
| 50 bp ladders | GeneRuler SM0373: 13 bands, 50–1,000 bp; ready-to-use. | 10515: 14 bands, 50–1,000 bp; stronger 250 and 500 bp reference bands. | Even with the same stated endpoints, band counts differ. Keep the correct band map with the image record.Thermo Scientific GeneRuler 50 bp DNA Ladder, ready-to-use SM0373Yeasen 10515: product specifications |
| DL5000 option | No direct one-to-one reference product is assigned to this option in this guide. | 10504: 9 bands, 100–5,000 bp; stronger 500 and 1,500 bp reference bands. | Consider this separate Yeasen band pattern when its positions suit the application; do not infer equivalence from the DL5000 name.Yeasen 10504: product specifications |
| Loading format | The GeneRuler catalogue numbers selected above are ready-to-use variants. | All three listed Yeasen ladders are premixed with loading buffer and also supply a separate 5× loading buffer. | Distinguish ready-to-use markers from other formulations when matching a purchase order.Thermo Scientific GeneRuler 1 kb DNA Ladder, ready-to-use SM0313Thermo Scientific GeneRuler 50 bp DNA Ladder, ready-to-use SM0373Yeasen 10504: product specificationsYeasen 10510: product specificationsYeasen 10515: product specifications |
Reference products and catalogue numbers
Find your current product, then review the relevant YEASEN option. Band positions and reference-band intensities differ; check the band map for the ladder you select.
- Thermo Scientific GeneRuler 1 kb DNA Ladder, ready-to-use
SM0314 · SM0313
- NEB 1 kb DNA Ladder
N3232S · N3232L
- Thermo Scientific GeneRuler 50 bp DNA Ladder, ready-to-use
SM0373
- NEB 50 bp DNA Ladder
N3236S · N3236L
- Takara Bio DL5,000 DNA Marker
3428A · 3428B
- Thermo Scientific FastRuler Middle Range DNA Ladder, ready-to-use
SM1113
- NEB Quick-Load 1 kb DNA Ladder
N0468S · N0468L
Labelled band positions
Nominal manufacturer labels, listed from smallest to largest. Use the exact product band map when labelling your gel image.
| Product | Band positions | Source |
|---|---|---|
| Yeasen 10504 DL5000 | 100, 250, 500, 750, 1,000, 1,500, 2,000, 3,000, 5,000 bp | Yeasen 10504: product specifications |
| Yeasen 10510 1 kb | 250, 500, 750, 1,000, 1,500, 2,000, 2,500, 3,000, 4,000, 5,000, 6,000, 8,000, 12,000 bp | Yeasen 10510: product specifications |
| Yeasen 10515 50 bp | 50, 100, 150, 200, 250, 300, 350, 400, 500, 600, 700, 800, 900, 1,000 bp | Yeasen 10515: product specifications |
Questions before switching products
Are all 50 bp ladders made up of bands at every 50 bp interval?
No. A product name alone is insufficient to reconstruct its band map. Use the manufacturer's complete table; the 50–1,000 bp ladders compared here have different band counts.
Section linkWhich ladder should I shortlist?
Start with the fragment range, then check the bands surrounding the expected size and the stronger reference bands. Review the 50 bp, 1 kb and DL5000 product pages for their complete band maps.
Section linkDoes T on a ladder pack mean PCR reactions?
No. It is the manufacturer's stated use-count format for the ladder. Compare it with your laboratory's consumption basis; do not treat it as the reaction count of a PCR master mix.
Section linkManufacturer sources
We supply the Yeasen products listed above. This guide compares manufacturer specifications; it is not an independent performance study. Reference products are identified for comparison and are not offered for sale here.
Find product documents and sources, or read our UK buying guide for ordering and delivery information.
Consult the current product documents for your application.
- Yeasen 10504: product specifications
- Yeasen 10510: product specifications
- Yeasen 10515: product specifications
- Thermo Scientific GeneRuler 1 kb DNA Ladder, ready-to-use SM0313
- Thermo Scientific GeneRuler 50 bp DNA Ladder, ready-to-use SM0373
Products are for research use only. Third-party trade marks belong to their respective owners; no affiliation or endorsement is implied. Similar applications do not establish identical composition, performance or compatibility.